It is broken down by micro-organisms if it reaches soil. The EPA also suggested that “human studies are inconclusive on the reproductive and developmental effects of styrene”. A study claims that 60-70% of the inhaled styrene is rapidly absorbed in the body. All rights reserved. Acute exposure to styrene causes nausea,a sense of inebriation, headache, burning sensation in the eyes, breathing difficulties, and could also lead to unconsciousness. It is also known as PVC gas (polyvinyl chloride), as it is used in the production of PVC. Hydrocarbons and benzenes are ring like structures that are formed due to various chemical bonds between carbons and hydrogens. The male rats that inhaled 750 ppm ethylbenzene also appeared to have an increase in testicular tumors, a type of tumor that occurs in nearly all aged rats of this strain. Acute lethality or serious poisoning in humans has rarely been reported in association with ethylbenzene exposure. Comments are moderated and will be published only after the site moderator’s approval. Other toxic effects noted in repeated-exposure studies in rodents reveal target organ effects specific to rodents that are not relevant to human health or occurred at very high dose levels of … The repeated exposure (non-cancer) systemic toxicity of ethylbenzene has been evaluated in laboratory animals in subchronic and chronic inhalation studies and subchronic oral studies. A 1995 study, however, showed an increase in the number of deaths due to neurological problems in workers who were exposed to styrene for a long period of time. Models (physiologically based pharmacokinetic or PBPK) have been developed that describe ethylbenzene disposition in rats, mice, and humans. Styrene is an easily machined and economically available plastic. BOOM spoke to an industry expert who opined that in the reactor, the compound is found in the liquid stage and is converted into gas when it passes through the pipes to the tanks. (Note: A previous version of the story said 13 people died. pic.twitter.com/WeCdrbddV1. There is no evidence that ethylbenzene is harmful to the immune system. Long-term effects include central nervous system dysfunction, depression, hearing loss and peripheral neuropathy (a numb feeling in the hands and feet). Ototoxicity indicated by alterations in brainstem auditory evoked responses and outer hair cell was found in a 13-week study in rats at concentrations of ≥ 200 ppm ethylbenzene. A styrene gas leak in the early hours of May 7, 2020 in Andhra Pradesh's Vizag (Vishakhapatnam) has affected over 5000 people and atleast ten people are reported to have died and over 300 hospitalised.

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