Figure 5. There are three types of epithelial cells that line the urinary tract. Transitional epithelial (or urothelial) cells come in various shapes. There are three main types of epithelial cells: Renal tubular: Also known as renal cells, an increase in renal tubular cells in the urine may indicate a kidney disorder. Cells from the deeper layers have much less cytoplasm and often tails or pointed cellular extensions (Fig. This means that the sample contains cells from the urethra (in men) or the vaginal opening (in women). 6). If there are squamous epithelial cells in your urine, it may mean your sample was contaminated. Epithelial cells naturally slough off from your body. Superficial cells resemble fried eggs with large, round nuclei and relevant amounts of cytoplasm (Fig. A urine test may show that you have “few,” “moderate,” or “many” epithelial cells in your urine. Squamous: These are large epithelial cells that come from the vagina and urethra. They are called transitional cells, renal tubular cells, and squamous cells. 5).

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